HORDB

ID: hor006458
Uniprot ID: Q32L79
Protein name: Insulin-like peptide INSL6 B chain
Gene name: INSL6
Organism: Bos taurus (Bovine)
Family: Insulin family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Bos (genus), Bovinae (subfamily), Bovidae (family), Pecora (infraorder), Ruminantia (suborder), Artiodactyla (order), Laurasiatheria (superorder), Boreoeutheria , Eutheria , Theria , Mammalia (class), Amniota , Tetrapoda , Dipnotetrapodomorpha , Sarcopterygii (superclass), Euteleostomi , Teleostomi , Gnathostomata , Vertebrata , Craniata (subphylum), Chordata (phylum), Deuterostomia , Bilateria , Eumetazoa , Metazoa (kingdom), Opisthokonta , Eukaryota (superkingdom),cellular organisms
GO MF: GO:0005179 hormone activity
GO BP: GO:0007165 signal transduction
GO CC: GO:0005576 extracellular region; GO:0005615 extracellular space

Sequence: LNDISRARRLCGQHLLHEIVKLCGDVNWSHVE
Length: 32(20-51)
Propeptide: MPRFLYLCLGLLLVRVSRELNDISRARRLCGQHLLHEIVKLCGDVNWSHVEKEKPFTQLLSQASEKVESFIPDRSESSQTTFPVWRRATNPVPTSASQEEAINNMKMQSLPEYQYKKANLPFKTRQEESSSSQDISPYIHEIIEFQKKNTNKIKTLSNLFWGNHPQRKRRGYSEKCCQKGCTKEELIIACLPYIDYENLRKHQQL
Signal peptide: MPRFLYLCLGLLLVRVSRE
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor006458_AF2.pdb

hor006458_ESM.pdb

Mass:	426542	Formula:	C160H260N52O46S2
Absent amino acids:	FMPTY	Common amino acids:	L
pI:	7.52	Basic residues:	7
Polar residues:	8	Hydrophobic residues:	12
Hydrophobicity:	-23.13	Boman Index:	-6583
Half-Life:	5.5 hour	Half-Life Yeast:	3 min
Half-Life E.Coli:	2 min	Aliphatic Index	115.63
Instability Index:	3017.81	Extinction Coefficient cystines:	5625
Absorbance 280nm:	181.45